Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 20;13:859730. doi: 10.3389/fimmu.2022.859730

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Guo, Wang, Jiang, Tang, Liu, Cao, Hu, Chen, Luo and Bo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The association between RFPL3S expression, methylation, and copy number in TCGA TGCT cohort. (A) The methylation level of RFPL3S in normal testicular tissues (N) and TGCT (T) tissues. (B) The high methylation regions were located at promoter (indicated by red and green arrows) and intron 4 (indicated by blue arrow). (C) RFPL3S methylation level was significantly negatively correlated with the expression level. (D) Correlation between RFPL3S methylation level and disease-free interval (DFI) and progression free interval (PFI) of TGCT cohort from TCGA. Patients with high RFPL3S methylation level had lower DFI and PFI. (E, F) Copy number was significantly positively correlated with the expression of RFPL3S. (G) Correlation between RFPL3S copy number and disease-free interval (DFI) and progression free interval (PFI) of TGCT cohort from TCGA. Patients with high RFPL3S copy number had higher DFI and PFI. CNV, copy number various. The UCSC XENA database was used to download the methylation data, expression data, and prognosis data of RFPL3S from the TCGA TGCT cohort. **P< 0.01.