Table 2.

Summary of serum hormones and BMI in NC-002

		Baseline		Day 57 = EOT
		n	Median	n	Median
FSH	Pa100MfxZ*	28	5.7	25	6.7
	Pa200MfxZ†	35	5.7	36	4.6
	HRZE‡	31	6.1	33	5.6
LH	Pa100MfxZ*	28	6.6	25	5.0
	Pa200MfxZ†	35	5.7	36	4.8
	HRZE‡	31	6.8	33	5.0
T	Pa100MfxZ*	28	12.0	26	18.5
	Pa200MfxZ†	35	14.4	36	18.8
	HRZE‡	31	14.7	33	32.4
BMI	Pa100MfxZ*	28	17.9	26	18.9
	Pa200MfxZ†	34	18.5	36	20.2
	HRZE‡	31	18.1	33	19.0

* Group treated with 100 mg/d Pa (drug-susceptible).

^† Group treated with 200 mg/d Pa (drug-susceptible and multidrug-resistant).

^‡ Group treated with standard of care (drug-susceptible).

BMI = body mass index; EOT = end-of-treatment; FSH = follicle stimulating hormone; Pa or PA-824 = pretomanid; MFX = moxifloxacin; Z = pyrazinamide; H = isoniazid; R = rifampin; E = ethambutol; LH = luteinizing hormone; T = testosterone (total).