Table 3.

Summary of serum FSH and BMI in NC-005 *

		Baseline		Day 29		Day 57 = EOT		Day 70
		n	Median	n	Median	n	Median	n	Median
FSH	DS-TB: BdqLoadPa200Z	45	5.0	43	5.7	37	5.6	35	5.8
	DS-TB: Bdq200Pa200Z	47	5.2	41	6.3	40	5.8	39	6.3
	DR-TB: Bdq200Pa200MfxZ	36	5.6	37	6.1	38	6.4	37	5.7
	DS-TB: HRZE	46	4.9	45	5.9	43	5.5	43	5.3
BMI	DS-TB: BdqLoadPa200Z	43	19.3	43	19.4	37	19.6	35	19.8
	DS-TB: Bdq200Pa200Z	45	19.2	41	19.7	40	20.0	39	20.2
	DR-TB: Bdq200Pa200MfxZ	36	18.0	37	18.3	38	18.8	37	18.4
	DS-TB: HRZE	46	17.9	45	18.7	43	18.9	43	19.1

* All patients in the Pa-containing arms (DS-TB and DR-TB) received 200 mg of Pa.

FSH = follicle stimulating hormone; BMI = body mass index; EOT = end-of-treatment; DS-TB = drug-susceptible TB; BDQ = bedaquiline; Pa = pretomanid; Z = pyrazinamide; DR-TB = drug-resistant TB; MFX = moxifloxacin; H = isoniazid; R = rifampin; E = ethambutol.