Table 2. Baseline level biochemical and circulating biomarkers in study subjects.
| Parameter | Placebo (n = 59) | Cholecalciferol (n = 58) | P values |
|---|---|---|---|
| Haemoglobin (g/dl) | 12.02±1.94 | 11.97±1.69 | 0.878 |
| eGFR (min/ml/1.73m2) | 34.63±12.25 | 35.77±12.37 | 0.723 |
| Albumin (g/dl) | 4.62±0.63 | 4.74±0.54 | 0.261 |
| Calcium (mg/dl) | 9.09±0.94 | 9.01±0.73 | 0.630 |
| Inorganic phosphorus (mg/dl) | 3.60 (3.07, 4.40) | 3.58 (3.01, 4.08) | 0.316 |
| Uric acid (mg/dl) | 7.66±2.37 | 8.01±2.32 | 0.435 |
| 25(OH)D (ng/ml) | 13.86 (9.19, 17.79) | 14.48 (9.34, 17.08) | 0.888 |
| 1,25 (OH)2 D(pg/ml) | 17.32 (10.58, 27.02) | 18.13 (11.58, 23.69) | 0.976 |
| Ang-1 (ng/ml) | 2.82 (0.90, 10.86) | 5.73 (1.62, 10.44) | 0.558 |
| Ang-2 (ng/ml) | 1.39 (0.92, 2.69) | 1.52 (0.90, 2.39) | 0.777 |
| VEGF (pg/ml) | 57.20 (17.40, 114.36) | 61.10 (26.57, 87.42) | 0.935 |
| VEGFR (pg/ml) | 400 (331, 494) | 387 (335, 515) | 0.931 |
| Tie-2 (ng/ml) | 20.71 (16.85, 24.87) | 20.86 (15.08, 27.08) | 0.881 |
| Ang-1/Ang-2 ratio | 1.50 (0.83, 5.80) | 3.20 (1.01, 8.68) | 0.185 |
Data presented as mean± standard deviation and median (25th, 75th percentile).
eGFR; estimated glomerular filtration rate, 25(OH)D; 25 hydroxy vitamin D, 1,25 (OH)2 D; 1,25 di-hydroxy vitamin D, Ang-1; Angiopoitein-1, Ang-2; Angiopoitein-2 VEGF; vascular endothelial growth factor-A, VEGFR; vascular endothelial growth factor receptor, Tie 2; tyrosine kinase receptor-2.