Fig 4. Bond graph representation of the EGFR pathway model.
Re components are numbered according to the steps in [30]. Each Ce or CS component is connected to a ‘0: u’ junction. Where a species participates in more than one reaction, new bonds are applied to its corresponding ‘0: u’ junction to share a common chemical potential (See R-PL where it is produced in reaction 5 and consumed in reaction 6). The chemostats in orange boxes are added to the reconstructed bond graph version.