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. 2022 Jun 3;17(6):e0267796. doi: 10.1371/journal.pone.0267796

Table 2. ELISA binding results to different spike protein variants.

Antibody Description S1 Binding EC50 ± Std Deviation (ng/mL) RBD Binding EC50 ± Std Deviation (ng/mL) S2 Binding EC50 (ng/mL)
mAb2130 WT 1.98 ± 0.04 2.68 ± 0.94 ND
mAb2130 YTE 15.53 ± 4.731 6.76 ± 5.33 ND
mAb2130 YTE-LALA 14.82 ±5.21 11.33 ± 2.01 ND
mAb2381 WT 1.50 ± 0.16 7.41 ± 0.37 ND
mAb2381 YTE 9.60 ± 2.39 8.53 ± 0.43 ND
mAb2381 YTE-LALA 10.73 ± 2.73 7.38 ± 1.26 ND
mAb2130 + mAb2381 YTE/LALA (ADM03820) 14.63 ± 2.95 7.80 ± 0.39 ND
mAb2130 + mAb2381 YTE (ADM03826) 12.69 ± 3.98 10.40 ± 0.52 ND

WT: Wild type sequence.

ND: No binding detected.