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. 2022 Jun 3;17(6):e0267796. doi: 10.1371/journal.pone.0267796

Table 3. Microneutralization analysis on various antibodies.

Antibody Sample IC50 (ng/mL) %CV
MAB2130 WT 9 NA1
MAB2130 YTE 17 34%
MAB2130 YTE-LALA 11 48%
MAB2381 WT 43 NA1
MAB2381 YTE 20 37%
MAB2381 YTE-LALA 15 41%
WT DP <7.5 NA
YTE DP 11 7%
YTE-LALA DP 6 66%

YTE DP: MAB2130 YTE combined with MAB2381 YTE (ADM03826).

YTE-LALA DP: MAB2130 YTE-LALA combined with MAB2381 YTE-LALA (ADM03820).

Multiple lots were generated for each antibody and combination. Values given are mean values with the correlation of variation.

1 Not Applicable. These samples were tested once and were similar to previously published results [50,51]. YTE and YTE LALA variants were tested using a validated assay.