Table 3. Exact classification results on the curated variant data.

	Acceptor Gain	Acceptor Loss	Donor Gain	Donor Loss
MES (Sliding Window)	0.00%	1.16%	2.33%	2.25%
SpliceAI	87.50%	77.10%	79.07%	78.93%
CI-SpliceAI	93.75%	78.55%	79.07%	82.02%

Comparison of the accuracy of predicting the exact location of the splice disruption on the 388 variants with known exact disruption coordinates. Except for donor gains, where CI-SpliceAI and the original SpliceAI have equal accuracy, CI-SpliceAI outperforms other models.