Table 4.

Clinical course of SARS-CoV-2 infection

Variables	REGEN-COV n=36	Control n=50	P valuea
Symptoms present at diagnosis
Subjective fever	4 (11)	4 (8)	.72
Cough	20 (56)	13 (26)	.005
Shortness of breath	8 (22)	8 (16)	.47
Myalgias	8 (22)	7 (14)	.32
Sore throat	4 (11)	3 (6)	.45
Congestion	5 (14)	6 (12)	1.00
Loss of taste or smell	1 (3)	6 (12)	.23
Nausea or vomiting	3 (8)	2 (4)	.65
Headache	3 (8)	1 (2)	.30
Chest pain	6 (17)	2 (4)	.06
Clinical findings present	11 (31)	8 (16)	.11
Temperature >100.4°F	7 (19)	2 (4)	.03
HR >110 BPM	7 (19)	6 (12)	.34
Hypotension <100/60 mm Hg	0	0
Hypoxia O2 <95%	6 (17)	6 (12)	.54
Leukocytosis or leukopenia	1 (3)	2 (4)	1.00
Fetal distress	1 (3)	0	.42
Abnormal chest imaging	7 (58.3)	6 (67)	1.00
Viral pneumonia	3 (25)	6 (67)	.09
Length of hospital admission for treatment of COVID-19 infection, n (%)	n=9	n=6	.51
<2 d	5 (56)	1 (17)
2–4 d	3 (33)	3 (50)
>4 d	1 (11)	2 (33)
Required ICU admission	1 (11)	2 (33)	.53
Required pharmacologic treatment for SARS-CoV-2	2 (6)	4 (8)	.70
Remdesivir or other antiviral	2 (6)	3 (6)	—
Tocilizumab	0	1 (2)	—
Other	0	1 (2)	—
Required oxygen support			1.00
Nasal cannula or high-flow	2 (6)	3 (6)	—
BiPAP	0	0	—
Mechanical ventilation	0	0	—
Required delivery for COVID-19	1 (3)	0	.42
Severe maternal morbidity event	3 (6)b	1 (2)c	.30

Data are number (percentage), unless otherwise specified.

BiPAP, bilevel positive airway pressure; BPM, beats per minute; HR, heart rate; ICU, intensive care unit.

^aTwo-sample t-test, chi-square, or exact chi-square tests were used, as appropriate. This P value reflects all clinical findings

^bThe first patient was admitted to the ICU for shock secondary to postpartum hemorrhage, the second for urosepsis, and the third (who also received intubation) for cardiac arrest of unknown etiology

^cOne patient was admitted to the ICU for COVID-19 pneumonia.

Levey. Outcomes of pregnant patients treated with REGEN-COV. Am J Obstet Gynecol MFM 2022.