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. Author manuscript; available in PMC: 2022 Jun 4.
Published in final edited form as: Nat Rev Drug Discov. 2021 Oct;20(10):730. doi: 10.1038/d41573-021-00158-9

Fig. 1 |. PIKfyve as a drug target.

Fig. 1 |

a | The phosphoinositide signalling pathway. Blue squares represent phosphoinositides. Blue arrows indicate the respective kinases, and grey arrows indicate the phosphatases. b | Structures of the PIKfyve inhibitors apilimod and YM201636.