Table 5.

Correlations between glioblastoma cyst fluid hormones and serum proteins and the volumes of tumors and cysts and degree of peri-tumoral edema

	Tumor volume		Cyst volume		Peritumoral edema
	r	p	r	p	r	p
IGF-1	0.11		0.38	0.061	0.08
Insulin	− 0.03		− 0.26		0.60	0.0016
Erythropoietin	0.03		− 0.08		− 0.04
Growth hormone	0.40	0.046	0.26		0.31
Testosterone	0.42	0.039	0.35	0.086	− 0.04
Estradiol	0.36	0.086	0.50	0.011	− 0.08
Triiodothyronine	− 0.18		− 0.14		− 0.27
SHBG	0.61	0.0014	0.60	0.0014	0.02
Albumin	0.48	0.015	0.20		0.25
Apolipoprotein A-I	0.26		0.28		0.02

Twenty-five cystic glioblastomas were analyzed with respect cyst fluid concentrations of hormones and serum proteins and tumor and cyst volumes and peri-tumoral edema. Data are correlation coefficients (r) and corresponding significant or near-significant p-values (p); Pearson’s test. Abbreviations: IGF-1: insulin-like growth factor 1; SHBG: sex hormone-binding globulin