Fig. 2.
CAV1 mRNA expression in primary breast cancer cell lines and tumors. (A) CAV1 correlations with Rs ≥ 0.3 in a subset of 809 breast cancers from TCGA. (B) Boxplots of CAV1 expression across subtypes as defined by Neve et al. [30]. and according to receptor status. (C)CAV1 expression (log2) across 51 individual breast cancer cell lines grouped according to Basal A (red), Basal B (gray), and Luminal (Blue) as defined by Neve et al. [30]. (D) CAV1 correlation within 1 881 breast tumors with eight gene modules (Stroma, Lipid, Immune response, mitotic checkpoint, mitotic progression, basal, early response, and steroid response) and corresponding correlation P-values from GOBO [28,29]. (E) STRING network analysis of the closest functional biological associations for CAV1 [30].