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. 2022 May 23;18(5):e1010557. doi: 10.1371/journal.ppat.1010557

Fig 3. Pathogenicity of LASV in T-cell depleted Stat1-KO.

Fig 3

Survival rate (A), body weight change (B), and body temperature (C) of T-cell-depleted Stat1-KO mice were plotted. Stat1-KO mice were injected with anti-CD4 and/or CD8 mAbs at 3 or 1 day prior to LASV infection in order to deplete CD4 and/or CD8 T-cells (n = 5). Mice in the isotype control group were injected with the isotype control mAb at 3 or 1 day prior to LASV infection (n = 20). Mice in the uninfected group were injected with the isotype control mAb at 3 or 1 day prior to PBS injection (n = 9).