Table 1.

Clinical data of 46 idebenone-treated and untreated arLHON patients

	Idebenone-treated 30 patients (29 males), 60 eyes		Untreated 16 patients (14 males), 32 eyes
	Recovery	No recovery	Recovery	No recovery
Patients	23	7	11	5
Eyes	46	14	22	10
Age at onset in years	19 (9–38)	21 (15–29)	20 (12–44)	19 (12–40)
Interval of disease onset between eyes in weeks	2.5 (0–32)	12 (0–20)	0 (0–48)	0 (0–24)
VA at nadir in best eye	1.4 (0.4–2.3)	1.5 (1.1–1.7)	1.7 (1–2)	1 (0.6–2)
VA at nadir in worst eye	1.4 (0.4–2.3)	1.7 (1–2)	1.4 (1.3–2)	1.5 (1–2.3)
VA at last examination in best eye	0.3 (0–1.7)	1.5 (1.1–1.7)	0.2 (0–1.3)	1 (0.7–2.0)
VA at last examination in worst eye	0.7 (0–1.9)	1.7 (1–2)	0.4 (0–1.3)	1.2 (0.3–2.3)
Duration of follow-up from onset in years	2 (0.5–11)	1 (1–14)	7 (1–13)	6 (1–19)

Data presented for 46 of the 56 identified arLHON patients with follow-up data available over at least 6-months following onset. Data are expressed as the median (range); disease onset refers to the first eye involved; visual acuity (VA) is expressed as logMAR and refers to the last examination.