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. 2022 Jun 3;12:9268. doi: 10.1038/s41598-022-13562-x

Table 3.

Logistic regression analysis to identify whether NLR and PLR are associated with depressive symptoms.

Males Females
aOR (95%CI) P-value aOR (95%CI) P-value
NLR, per 1 increase 1.570 (1.120–2.220) 0.009* 0.871 (0.652–1.160) 0.349
PLR, per 1 increase 1.000 (0.994–1.010) 0.899 1.000 (0.997–10.10) 0.520
Age
 < 45 Reference Reference
45 ≤ , < 65 0.546 (0.285, 1.050) 0.069 0.668 (0.392, 1.140) 0.137
65 ≤ , < 75 0.763 (0.344, 1.690) 0.504 0.912 (0.463, 1.800) 0.790
75 ≤  0.359 (0.111, 1.160) 0.087 0.734 (0.289, 1.860) 0.516
BMI
18.5 ≤ , < 25 Reference Reference
 < 18.5 0.355 (0.043, 2.920) 0.335 1.470 (0.780, 2.790) 0.233
25 ≤ , < 30 0.674 (0.352, 1.290) 0.235 1.400 (0.812, 2.420) 0.225
30 ≤  0.837 (0.279, 2.510) 0.751 0.822 (0.258, 2.620) 0.741
AST, per 1 U/L increase 0.951 (0.900–1.010) 0.077
ALT, per 1 U/L increase 1.020 (0.986–1.050) 0.247
Hypertension 1.060 (0.523–2.130) 0.881 1.340 (0.766–2.340) 0.305
DM 1.030 (0.355–2.960) 0.964 0.565 (0.151–2.110) 0.397
Dyslipidemia 1.080 (0.446–2.600) 0.871 1.360 (0.706–2.630) 0.357
CAD 0.476 (0.056–4.040) 0.496
Stroke 1.000 (1.000–1.000) 0.551 1.000 (1.000–1.000) 0.596
Alcohol drinker 0.548 (0.322–0.930) 0.026*

*P < 0.05. As none of the VIF values were up to 10, there was no collinearity in the model. AUC values for males and females were 0.675 and 0.603, respectively. Hosmer–Lemeshow test: P = 0.36, which means that the fitness of this model was good.

aOR adjusted odds ratio, ALT alanine transferase, AST aspartate transferase, BMI body mass index, CAD coronary artery disease, DM diabetes mellitus, NLR neutrophil–lymphocyte ratio, PLR platelet-lymphocyte ratio.