Fig. 3.

Effects of (S)-ketamine on temporal discrimination. (A) Mean ± SEM proportion of choices of the 12-s B lever as a function of stimulus duration. (S)-Ketamine at the dose of 15 mg/kg shifted the psychometric curve to the right and down, suggesting time underestimation, expressed also as increased mean T₅₀ (B). The same dose, however, reduced median of the slope function (C); increased the median of the difference limen (D); as well as the median of the Weber fraction (E). Symbols: *P < 0.05 versus vehicle. Wherever possible, the number of animals is shown on the bottom of the bar