Table 1.
Sequence of drug testing in the temporal discrimination task (TDT)
Week(s) of testing | Treatment |
---|---|
1–4 | “Low” doses of (R)-ketamine (0, 7.5, 15 mg/kg) |
“Low” doses of (S)-ketamine (0, 3.5, 7.5 mg/kg) | |
5–6 | Wash-out and training with vehicle |
7–8 | Psilocybin (0, 0.3, 1 mg/kg) |
8–9 | Wash-out and training with vehicle |
9–10 | Psilocin (0, 0.22, 0.72 mg/kg) |
11–12 | Wash-out and training with vehicle |
13–14 | Norpsilocin (0, 0.22, 0.72 mg/kg) |
15 | Wash-out and training with vehicle |
16–18 | “High” doses of (R)-ketamine (0, 30 mg/kg) |
“High” doses of (S)-ketamine (0, 15 mg/kg) |