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. 2022 May 27;2022:8267891. doi: 10.1155/2022/8267891

Figure 5.

Figure 5

FAM84B overexpression reversed antitumor effects of miR-205-5p in GC. The experiments were performed in three groups: (1) NC mimic + Lv-NC; (2) miR-205-5p mimic + Lv-NC; and (3) miR-205-5p mimic + Lv-FAM84B. (a) The recombinant lentivirus vectors that contained FAM84B full sequence or NC sequence were transfected into AGS and SGC-7901 cells, and FAM84B expression was detected by qRT-PCR. ∗∗∗p <0.001 vs. Lv-NC (b) Cell viability of transfected AGS and SGC-7901 cells was detected by using the CCK-8 assay. (c) Colony formation of transfected AGS and SGC-7901 cells was detected. (d) Cell apoptosis of transfected AGS and SGC-7901 cells was detected by flow cytometry. (e) Transwell assay investigated the migration and invasion activities of transfected cells. ∗∗p <0.01 and ∗∗∗p <0.001 vs. NC mimic; ∗∗p <0.01 vs. MiR-205-5p mimic + Lv-NC. All experiments were performed in triplicate and repeated at least three times.