Table 3.

Risk factors of the improvement of diastolic function.

Variables	Univariate		Multivariate
	HR	P value	HR	P value
MAP	0.31 (0.29–0.39)	0.033	0.062 (0.031∼0.088)	0.043
HR (bpm)	0.006 (0.002∼0.013)	0.007	0.008 (0.003–0.014)	0.037
EGFR	0.006 (0.002–0.014)	0.122	—	—
Medications	0.01 (0.009∼0.015)	0.625	—	—

eGFR: estimated glomerular filtration rate; HR: heart rate; MAP: mean blood pressure. Medications referred to the changes of drugs categories.