Table 1.

Literature review on coexistence of rheumatoid arthritis and ankylosing spondylitis.

Author	No.	Sex	Age (years)	1st symptom	Onset (years)	1st disease	Duration (years)	Nodules	RF	Ac. CCP	HLA B-27	Lumbar pain	SI	Sind	Eros	Uveitis	Extra-art involv
Wilkinson and Bywaters	1	M	55	Arthritis	22	RA	33	+	+	NA	NA	+	+	NS	+	+	0
Martel and Duff	2	M	47	Arthritis	18	RA	29	0	+	NA	NA	+	+	0	+	0	0
	3	F	32	Arthritis	30	RA	2	+	+	NA	NA	+	+	+	+	0	0
	4	F	27	Arthritis	15	RA	12	+	+	NA	NA	0	+	+	+	0	0
	5	F	42	Arthritis	24	RA	18	+	+	NA	NA	0	+	NS	+	0	+
	6	M	52	Arthritis	21	RA	31	+	+	NA	NA	0	+	+	+	0	+
	7	M	37	Arthritis	29	RA	8	0	0	NA	NA	+	+	NS	+	+	+
	8	M	54	Arthritis	43	RA	9	+	+	NA	NA	+	0	NS	+	0	0
London and Bland	9	M	26	Arthritis	14	RA	12	+	NS	NA	NA	+	+	NS	NS	0	0
Rosenthal et al. [8]	10	M	73	Uveitis	22	AE	51	+	+	NA	NA	+	+	+	NS	+	+
Husskisson et al. [37]	11	M	80	L. pain	25	AE	55	+	+	NA	NA	+	+	+	+	+	0
Valkenburgh et al. [9]	12	F	45	Arthritis	36	RA	9	+	+	NA	NA	+	+	NS	+	+	+
Luthrah et al. [10]	13	M	59	L. pain	34	AE	25	+	+	NA	+	+	+	+	+	0	0
	14	M	65	L. pain	48	AE	17	+	+	NA	+	+	+	+	+	0	0
Querol et al. [11]	15	M	40	L. pain	18	AE	22	0	0	NA	+	+	+	0	0	0	0
	16	F	46	L. pain	27	AE	19	0	+	NA	+	+	+	0	+	0	0
	17	M	51	L. pain	25	AE	26	+	0	NA	+	+	+	+	0	0	0
	18	M	50	L. pain	42	AE	8	0	0	NA	+	+	+	+	0	0	0
	19	M	53	L. pain	41	AE	12	+	+	NA	+	+	+	+	+	0	0
	20	M	17	L. pain	15	AE	2	0	+	NA	+	0	+	0	+	0	0
	21	M	28	L. pain	15	AE	13	0	0	NA	+	+	+	0	0	0	0
Fallet et al. [35]	22	M	64	L. pain	30	AE	34	+	+	NA	+	+	+	+	+	0	0
	23	M	68	Arthritis	29	RA	39	0	+	NA	+	NS	+	NS	+	+	0
	24	F	68	Arthritis	65	RA	3	+	+	NA	+	0	+	NS	0	0	0
	25	M	54	Arthritis	40	RA	14	+	+	NA	+	+	+	NS	+	0	0
	26	M	67	Arthritis	57	RA	10	0	+	NA	0	+	+	+	+	0	0
	27	F	75	Arthritis	63	RA	12	0	+	NA	+	+	+	+	+	0	0
	28	F	58	Uveitis	42	RA	16	0	+	NA	+	0	+	NS	+	+	0
	29	M	68	L. pain	29	AE	39	0	+	NA	+	+	+	NS	+	0	0
	30	M	44	Myalgias	36	AE	8	+	+	NA	+	+	+	NS	+	0	0
Good et al. [12]	31	M	NS	L. pain	29	AE	NS	0	+	NA	+	+	+	+	+	0	0
	32	M	NS	L. pain	20	AE	NS	0	+	NA	+	+	+	+	+	0	0
	33	M	NS	L. pain	34	AE	NS	0	+	NA	+	+	+	0	+	0	0
Clayman and Reinertsen	34	M	48	L. pain	21	AE	27	+	+	NA	+	+	+	+	0	0	0
Espinoza et al. [14]	35	M	53	L. pain	47	AE	6	+	+	NA	+	+	+	NS	+	0	0
Major et al. [15]	36	M	64	L. pain	28	AE	36	+	+	NA	+	+	+	+	+	0	0
	37	M	61	L. pain	NS	AE	NS	0	+	NA	+	+	+	+	+	0	0
Lemmer and Irby	38	M	51	L. pain	26	AE	25	+	+	NA	+	+	+	+	+	0	+
Alexander et al. [17]	39	M	55	Arthritis	32	RA	23	+	+	NA	+	+	+	NS	+	0	+
	40	M	61	Arthritis	54	RA	7	+	+	NA	+	0	+	+	+	0	+
	41	M	NS	NS	NS	NS	NS	+	+	NA	0	NS	+	NS	0	0	0
	42	M	NS	NS	NS	NS	NS	+	+	NA	0	NS	+	NS	+	0	0
	43	M	NS	NS	NS	NS	NS	+	+	NA	+	NS	+	NS	+	0	0
Lavery et al. [18]	44	M	60	L. pain	18	AE	42	+	+	NA	+	+	+	NS	+	+	+
Alarcón Segovia and Martínez-Cordero	45	M	70	L. pain	NS	NS	NS	+	+	NA	+	+	+	+	+	0	0
Serrano et al. [20]	46	M	35	NS	22	RA	13	NS	+	NA	+	+	+	NS	NS	0	+
Fallet et al. [21]	47	M	52	Arthritis	25	RA	27	0	+	NA	+	+	+	+	+	+	+
	48	M	60	L. pain	48	AE	12	+	+	NA	+	+	+	+	+	0	0
	49	M	61	Arthritis	40	NS	11	0	+	NA	+	0	+	0	+	0	0
	50	M	56	L. pain	22	AE	34	0	+	NA	+	+	+	+	+	+	+
	51	M	66	Arthritis	61	RA	5	+	+	NA	+	+	+	0	+	0	0
	52	M	71	L. pain	21	AE	50	+	+	NA	+	+	+	+	+	0	0
	53	M	49	Arthritis	35	RA	14	0	+	NA	+	+	+	0	+	0	0
	54	F	83	Arthritis	69	RA	14	0	+	NA	+	+	+	+	+	0	0
Helfgott et al. [22]	55	M	77	L. pain	39	AE	38	+	+	NA	+	+	+	+	+	0	0
Sattar et al. [23]	56	M	35	L. pain	25	AE	10	0	+	NA	0	+	+	+	+	+	+
Martínez-Cordero et al. [24]	57	M	38	Arthritis	28	RA	10	NS	+	NA	+	+	+	+	+	0	0
Ferreiro Seoane et al. [25]	58	M	44	L. pain	31	AE	13	+	+	NA	+	+	+	NS	+	0	+
Toussirot and Acquaviva	59	M	48	Arthritis	22	RA	26	+	+	NA	0	0	+	0	+	0	0
	60	M	77	Arthritis	35	RA	42	0	+	NA	0	+	+	+	+	0	0
	61	F	27	Arthritis	19	RA	8	0	+	NA	+	+	+	0	+	0	0
Genc et al. [27]	62	F	62	Arthritis	52	RA	10	NS	0	NA	+	+	+	+	+	0	+
Guo et al. [28]	63	F	30	L. pain	23	AE	7	0	+	+	+	+	+	NS	+	0	0
Baksay et al. [29]	64	F	57	L. pain	25	AE	32	NS	+	+	+	+	+	+	+	0	0
Feijo et al. (2011)	65	F	65	L. pain	64	AE	1	0	+	+	+	+	+	+	+	0	0
Aghdashi et al. [31]	66	F	70	Arthritis	58	RA	12	NS	+	+	+	0	+	+	+	0	0
Dundar et al. [32]	67	M	63	L. pain	51	RA	12	NS	+	+	NS	+	+	NS	+	0	0
Koca et al. [38]	68	F	38	L. pain	38	RA	1	0	+	+	0	+	+	0	0	0	0
Barczynska et al. [33]	69	F	55	Arthritis	35	RA	20	+	+	+	+	+	+	+	+	0	0
	70	M	56	L. pain	34	AE	22	NS	+	0	+	+	+	+	+	0	0
	71	M	65	NS	NS	NS	NS	NS	+	0	+	+	+	+	+	0	0
Baccouche et al. [34]	72	F	21	L. pain	20	AE	1	0	+	+	+	+	+	+	+	0	0
Sargin and Gurer	73	F	47	L. pain	45	RA	2	0	NS	NS	NS	+	+	NS	NS	0	0
Haridas and Kiran	74	F	32	Arthritis	32	AR	1	0	+	+	+	+	+	NS	NS	0	0
Flores-Robles et al. (2020)	75	M	55	L. pain	41	AE	14	0	+	+	+	+	+	+	0	0	0
	76	F	43	Arthritis	35	RA	8	0	+	+	+	+	+	0	+	0	0
	77	F	64	Arthritis	51	RA	13	0	+	+	+	0	+	0	0	0	0
	78	M	57	Arthritis	28	RA	29	+	+	+	+	0	+	0	+	0	0
	79	M	64	L. pain	49	AE	15	0	+	+	+	+	+	+	0	0	0
	80	M	63	Arthritis	47	RA	16	0	+	+	+	+	+	+	+	0	0
	81	F	75	Arthritis	70	RA	5	0	+	+	+	+	+	+	+	0	0

Ac. CCP: citrullinated peptide antibodies; AE: ankylosing spondylitis; Eros: radiographic erosions on hands and/or feet; extra-art involv: extra-articular involvement; F: female; L. pain: lumbar pain; M: male; NA: not applicable; NS: not specified by the author; RA: rheumatoid arthritis; RF: rheumatoid factor; SI: radiological sacroiliitis; Sind: spine syndesmophytes; sign +: existence/positive; sign 0: absence/negative.