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. Author manuscript; available in PMC: 2023 Jun 15.
Published in final edited form as: Biol Psychiatry. 2022 Jan 10;91(12):1019–1028. doi: 10.1016/j.biopsych.2022.01.002

Table 1: Average Weekly Alcohol Intake Prior to Chemogenetic Inhibition of CeADYN Neurons.

Alcohol intake (g/kg) in mice expressing hM4Di or mCherry in CeADYN neurons during Baseline and Test weeks prior to challenge with vehicle or CNO (3 mg/kg) during Test 3. Values are mean ± s.e.m.

AAV Group Baseline Test 1 Test 2
hM4Di CTL 1.48 ± 0.12 1.44 ± 0.14 1.49 ± 0.16
FSS 1.57 ± 0.13 1.78 ± 0.12 1.94 ± 0.17
CIE 1.49 ± 0.18 1.95 ± 0.26* 1.84 ± 0.20*
CIE+FSS 1.54 ± 0.15 2.13 ± 0.25* 2.54 ± 0.22*

mCherry CTL 1.62 ± 0.17 1.72 ± 0.17 1.33 ± 0.13
FSS 1.49 ± 0.11 1.56 ± 0.19 1.65 ± 0.06
CIE 1.61 ± 0.11 2.53 ± 0.19* 2.37 ± 0.20*
CIE+FSS 1.73 ± 0.13 2.83 ± 0.34* 2.57 ± 0.32*
*

differs from respective Baseline levels (p< 0.05).