Table 1: Average Weekly Alcohol Intake Prior to Chemogenetic Inhibition of CeADYN Neurons.
AAV | Group | Baseline | Test 1 | Test 2 |
---|---|---|---|---|
hM4Di | CTL | 1.48 ± 0.12 | 1.44 ± 0.14 | 1.49 ± 0.16 |
FSS | 1.57 ± 0.13 | 1.78 ± 0.12 | 1.94 ± 0.17 | |
CIE | 1.49 ± 0.18 | 1.95 ± 0.26* | 1.84 ± 0.20* | |
CIE+FSS | 1.54 ± 0.15 | 2.13 ± 0.25* | 2.54 ± 0.22* | |
| ||||
mCherry | CTL | 1.62 ± 0.17 | 1.72 ± 0.17 | 1.33 ± 0.13 |
FSS | 1.49 ± 0.11 | 1.56 ± 0.19 | 1.65 ± 0.06 | |
CIE | 1.61 ± 0.11 | 2.53 ± 0.19* | 2.37 ± 0.20* | |
CIE+FSS | 1.73 ± 0.13 | 2.83 ± 0.34* | 2.57 ± 0.32* |
differs from respective Baseline levels (p< 0.05).