Table 2.

Proteins up- or downregulated in PNS myelin from 17-month-old Fa2h^−/− mice

Gene	Accession	Description	log(2)FC	p-value	adj. p-value
Mgll	O35678	Monoglyceride lipase	2.0417	0.00065	0.04408
Aoc3	O70423	Membrane primary amine oxidase	1.9773	0.00173	0.08416
Cd36	Q08857	Platelet glycoprotein 4	1.7469	0.00198	0.08434
Lyz1	P17897	Lysozyme C-1	1.5559	0.00001	0.00823
Lgals3	P16110	Galectin-3	1.2117	0.00004	0.01364
H2-K1	P01901	H-2 class I histocompatibility antigen. K-B alpha chain	1.0319	0.00106	0.06548
Slc27a1	Q60714	Long-chain fatty acid transport protein 1	0.9612	0.00285	0.09704
Epb41l2	O70318	Band 4.1-like protein 2	0.7338	0.00014	0.03057
Pals2	Q9JLB0	Protein PALS2 / Mpp6	0.6964	0.00022	0.03057
Cadm4	Q8R464	Cell adhesion molecule 4	0.6916	0.00305	0.09890
Anxa1	P10107	Annexin A1	0.6677	0.00052	0.04379
Fkbp3	Q62446	Peptidyl-prolyl cis–trans isomerase FKBP3	-0.6819	0.00261	0.09704
Ran	P62827	GTP-binding nuclear protein Ran	-0.7083	0.00050	0.04379
Cdv3	Q4VAA2	Protein CDV3	-0.7100	0.00145	0.07614
Plcb3	P51432	1-phosphatidylinositol 4.5-bisphosphate phosphodiesterase beta-3	-0.7561	0.00192	0.08433
Chmp1b1	Q99LU0	Charged multivesicular body protein 1b-1	-0.7998	0.00141	0.07614
Atp6v1c1	Q9Z1G3	V-type proton ATPase subunit C 1	-0.8616	0.00058	0.04379
Cast	P51125	Calpastatin	-0.9294	0.00271	0.09704
Sbds	P70122	Ribosome maturation protein SBDS	-1.0121	0.00022	0.03057
Tppp	Q7TQD2	Tubulin polymerization-promoting protein	-1.0368	0.00054	0.04379
Igkc	P01837	Immunoglobulin kappa constant	-1.4922	0.00284	0.09704

Log(2)FC log(2)-fold change (Fa2h^−/−:Fa2h^+/+), adj p value adjusted p value according to Benjamini and Hochberg [28]. Known myelin proteins (according to Table 1 in Siems et al. [28]) are highlighted in bold font