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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Curr Opin Pharmacol. 2022 Mar 17;64:102204. doi: 10.1016/j.coph.2022.102204

Table 2:

Regulatory genetic sequences used in non-human primate (NHP) studies to drive transgene expression using viral vectors (only studies in which the use of the sequence was verified in NHPs are included)

Regulatory sequence Cell-type specificity Transgene expressed References
Human Synapsin1 (SYN) Neurons Opsins, chemogenetic receptors, fluorescent proteins Numerous, see e.g. Table 1
CaMKIIα Mainly excitatory projection neurons, but also in some interneurons Opsins, fluorescent proteins [8183]
Tyrosine hydroxylase (TH) Catecholaminergic neurons Opsins, chemogenetic receptors, fluorescent proteins [16,35,44]
Dlx5/6 Telencephalic GABAergic neurons GFP
Opsins
[84,85]
Parvalbumin (PV) PV-expressing GABAergic neurons Opsins [85]
E2 PV-expressing GABAergic neurons Opsins [43]
GFAP Astrocytes GFP [86]
L7 Purkinje cells Opsins [87]
ChAT Cholinergic interneurons GFP [88]