Table 2.
SOD, GSH-Px, AOPP, MDA, Conjugated diene, 8-Isoprostaglandin F2α activity of lenses and aqueous humor
| Biomarkers | Lenses | Aqueous humor | ||||
|---|---|---|---|---|---|---|
| Diabetic Cataract | Non Diabetic Cataract |
P value | Diabetic Cataract | Non Diabetic Cataract |
P value | |
|
SOD* (Units/mg tissue) |
2.739 ± 0.24 | 4.794 ± 0.30 | < 0.001 | 0.244 ± 0.006 | 0.266 ± 0.005 | 0.038 |
|
GSH-Px* (per Min/mg of tissue) |
0.446 ± 0.02 | 0.562 ± 0.02 | 0.002 | 0.446 ± 0.02 | 19.9 ± 0.52 | 0.017 |
|
AOPP* (Micro mols/ml) |
0.190 ± 0.002 | 0.170 ± 0.002 | 0.0001 | 3.398 ± 0.21 | 2.697 ± 0.16 | 0.007 |
| MDA* (Micro mols/g) | 83.52 ± 2.89 | 58.84 ± 1.61 | < 0.0001 | 116.2 ± 3.20 | 81.51 ± 3.51 | < 0.0001 |
| Conjugated diene* (OD at 234 nm) | 0.530 ± 0.02 | 0.400 ± 0.02 | 0.001 | 0.359 ± 0.02 | 0.281 ± 0.01 | 0.021 |
| 8-Isoprostaglandin#F2α (pg/ml) | 197.8 ± 21.43 | 51.69 ± 6.83 | 0.0001 | 4320 ± 496 | 2886.38 ± 386 | 0.027 |
Student’s t-test was used to compare the differences and data were described as Mean ± SD. *N = 92, #N = 35
SOD- Superoxide dismutase, GSH-Px—Glutathione peroxidsae, AOPP- Advanced oxidation protein products, MDA- Malondialdehyde