Table 1.

The time course of signs of toxicity in mice treated with EMZFP-2000, 3000, and 5000 mg kg^-1 b.w. and 2000 mg kg^-1 b.w. for fractions of EMZFP.

Observations	At 3 h	At 24 h	At 72 h
Physical activity	N	N	N
Skin and fur	N	N	N
Eyes and mucous membranes	N	N	N
Behavioral pattern	N	N	N
Respiratory	N	N	N
Circulatory	N	N	N
Autonomic profile	N	N	N
Neurologic profile	N	N	N
Sleep	N	N	N
Diarrhea	N	N	N
Tremors	N. O.*	N. O.*	N. O.*
Mortality	N. O.*	N. O.*	N. O.*

N normal, N.O.* not observed