Table 2.
Characteristics of the studies included in the meta-analysis
| First author and reference | Year | Country | Type of diabetes | n (cases/controls) | Cases | Controls | HWE | ||
|---|---|---|---|---|---|---|---|---|---|
| Genotypes | Alleles | Genotypes | Alleles | ||||||
| rs1617640 | 9117 (4462/4655) | TT/TG/GG | T/G | TT/TG/GG | T/G | ||||
| Tong (1) [10] | 2008 | USA | T2DM | 613 (374/239) | 150/172/52 | 472/276 | 66/127/46 | 259/219 | Yes |
| Tong (2) [10] | 2008 | USA | T1DM | 1439 (865/574) | 335/419/111 | 1089/641 | 148/307/119 | 603/545 | Yes |
| Tong (3) [10] | 2008 | USA | T1DM | 520 (379/141) | 139/180/60 | 458/300 | 35/78/28 | 148/134 | Yes |
| Abhary (1) [11] | 2010 | Australia | T2DM | 333 (170/163) | 65/78/27 | 208/132 | 64/88/11 | 216/110 | No |
| Abhary (2) [11] | 2010 | Australia | T1DM | 167 (102/65) | 40/44/18 | 124/80 | 24/30/11 | 78/52 | Yes |
| Balasubbu [12] | 2010 | India | T2DM | 702 (344/358) | 31/163/150 | 225/463 | 30/171/157 | 231/485 | Yes |
| Yang [14] | 2014 | China | T2DM | 491 (211/280) | 146/55/10 | 347/75 | 182/82/16 | 446/114 | Yes |
| Song [16] | 2015 | China | T2DM | 782 (444/338) | 293/138/13 | 724/164 | 225/98/15 | 548/128 | Yes |
| Fan [17] | 2016 | China | T2DM | 1193 (397/796) | 208/161/28 | 577/217 | 468/302/26 | 1238/354 | No |
| Montesanto [18] | 2018 | Italy | T2DM | 433 (107/326) | 51/42/14 | 144/70 | 140/145/41 | 425/227 | Yes |
| Kaur [19] | 2021 | India | T2DM | 614 (302/312) | 125/129/48 | 379/225 | 122/116/74 | 360/264 | No |
| Mankoc Ramus [20] | 2021 | Slovenia | T2DM | 797 (217/580) | 70/96/51 | 236/198 | 180/305/95 | 665/495 | Yes |
| Sesti (1) | Present study | Brazil | T2DM | 731 (422/309) | 183/194/45 | 560/284 | 132/147/30 | 411/207 | Yes |
| Sesti (2) | Present study | Brazil | T2DM | 302 (128/174) | 47/65/16 | 159/97 | 76/74/24 | 226/122 | Yes |
| rs507392 | 5023 (2281/2742) | TT/TC/CC | T/C | TT/TC/CC | T/C | ||||
| Abhary (1) [11] | 2010 | Australia | T2DM | 332 (170/162) | 65/78/27 | 208/132 | 63/88/11 | 214/110 | No |
| Abhary (2) [11] | 2010 | Australia | T1DM | 167 (102/65) | 40/44/18 | 124/80 | 24/30/11 | 78/52 | Yes |
| Yang [14] | 2014 | China | T2DM | 496 (216/280) | 141/65/10 | 347/85 | 181/81/18 | 443/117 | No |
| Song [16] | 2015 | China | T2DM | 782 (444/338) | 281/149/14 | 711/177 | 217/97/24 | 531/145 | No |
| Fan [17] | 2016 | China | T2DM | 1193 (397/796) | 202/161/34 | 565/229 | 463/305/28 | 1231/361 | No |
| Montesanto [18] | 2018 | Italy | T2DM | 420 (104/316) | 48/43/13 | 139/69 | 130/146/40 | 406/226 | Yes |
| Kaur [19] | 2021 | India | T2DM | 614 (302/312) | 138/124/40 | 400/204 | 132/106/74 | 370/254 | No |
| Sesti (1) | Present study | Brazil | T2DM | 722 (418/304) | 181/192/45 | 554/282 | 126/148/30 | 400/208 | Yes |
| Sesti (2) | Present study | Brazil | T2DM | 297 (128/169) | 47/65/16 | 159/97 | 72/72/25 | 216/122 | Yes |
| rs551238 | 5031 (2279/2752) | AA/AC/CC | A/C | AA/AC/CC | A/C | ||||
| Abhary (1) [11] | 2010 | Australia | T2DM | 333 (170/163) | 65/78/27 | 208/132 | 64/88/11 | 216/110 | No |
| Abhary (2) [11] | 2010 | Australia | T1DM | 167 (102/65) | 40/44/18 | 124/80 | 24/30/11 | 78/52 | Yes |
| Yang [14] | 2014 | China | T2DM | 494 (216/278) | 141/65/10 | 347/85 | 182/79/17 | 443/113 | No |
| Song [16] | 2015 | China | T2DM | 774 (439/335) | 286/140/13 | 712/166 | 219/92/24 | 530/140 | No |
| Fan [17] | 2016 | China | T2DM | 1193 (397/796) | 203/156/38 | 562/232 | 452/299/45 | 1203/389 | Yes |
| Montesanto [18] | 2018 | Italy | T2DM | 428 (106/322) | 51/42/13 | 144/68 | 138/143/41 | 419/225 | Yes |
| Kaur [19] | 2021 | India | T2DM | 614 (302/312) | 130/125/47 | 385/219 | 123/117/72 | 363/261 | No |
| Sesti (1) | Present study | Brazil | T2DM | 731 (419/312) | 181/188/50 | 550/288 | 129/150/33 | 408/216 | Yes |
| Sesti (2) | Present study | Brazil | T2DM | 297 (128/169) | 46/66/16 | 158/98 | 71/73/25 | 215/123 | Yes |
SNP single nucleotide polymorphism, T2DM type 2 diabetes mellitus, T1DM type 1 diabetes mellitus, HWE Hardy–Weinberg equilibrium