Table 2.
Comparison of CMR‐derived parameters among normal controls, NIDCM patients with and without T2DM
| Normal controls (n = 80) | NIDCM (T2DM −) (n = 342) | NIDCM (T2DM +) (n = 93) | |
|---|---|---|---|
| LV geometry and function | |||
| LVEDVi (mL/m2) | 75.29 ± 15.05 | 163.15 (136.51, 200.08) * | 160.58 (135.28, 202.25) * |
| LVESVi (mL/m2) | 28.07 ± 8.20 | 126.64 (94.97, 159.57) * | 128.83 (98.16, 163.34) * |
| LVSVi (mL/m2) | 47.23 ± 9.81 | 37.81 (27.55, 48.25) * | 34.30 ± 12.82 *,§ |
| LVEF (%) | 62.94 ± 6.65 | 22.79 (16.90, 30.32) * | 21.75 ± 9.87 * |
| LVMI (g/m2) | 42.73 ± 6.65 | 70.56 (59.95, 82.50) * | 81.25 (61.57, 94.01) *, § |
| RVEF (%) | 56.09 ± 7.06 | 32.30 (20.42, 46.77) * | 27.12 (13.42, 41.11) *, § |
| LV remodelling index, g/mL | 0.57 ± 0.11 | 0.42 (0.36, 0.50) * | 0.46 (0.40, 0.57) *, § |
| Presence of LGE, n (%) | – | 238 (70) | 61 (66) |
| LV PS (%) | |||
| GRPS | 34.00 (29.98, 40.93) | 8.58 (5.91, 12.95) * | 6.42 (4.66, 11.17) *, § |
| GCPS | − 20.61 ± 2.60 | − 6.99 (− 9.45, − 5.32) * | − 5.53 (− 8.14, 4.12) *, § |
| GLPS | − 14.14 ± 2.22 | − 5.59 (− 7.34, − 4.23) * | − 4.54 (− 5.89, − 3.22) *, § |
| LV PSSR (1/s) | |||
| Radial | 2.10 (1.64, 2.54) | 0.59 (0.43, 0.83) * | 0.53 (0.36, 0.75) * |
| Circumferential | − 1.07 (− 1.18, − 0.92) | − 0.44 (− 0.56, − 0.33) * | − 0.38 (− 0.50, − 0.30) *, § |
| Longitudinal | − 0.79 (− 0.88, − 0.69) | − 0.40 (− 0.52, − 0.31) * | − 0.33 (− 0.47, − 0.26) *, § |
| LV PDSR (1/s) | |||
| Radial | − 2.50 (− 3.10, − 2.00) | − 0.61 (− 0.93, − 0.45) * | − 0.56 (− 0.90, 0.38) * |
| Circumferential | 1.26 ± 0.24 | 0.49 (0.36, 0.66) * | 0.44 (0.31, 0.60) *, § |
| Longitudinal | 0.91 ± 0.24 | 0.42 (0.33, 0.55) * | 0.36 (0.26, 0.48) *, § |
All values are presented as n (%) or median (Q1-Q3). “ − ” indicates the direction of strains. LV left ventricular, EF ejection fraction, LVEDVi left ventricular end-diastolic volume index, LVESVi left ventricular end- systolic volume index, LVSVi left ventricular stroke-volume index, LVMI left ventricular mass index, RVEF right ventricular ejection fraction, LGE late gadolinium enhancement, PS peak strain, GRPS global radial peak strain, GCPS global circumferential peak strain, GLPS global longitudinal peak strain, PSSR peak systolic strain rate, PDSR peak diastolic strain rate, LGE late gadolinium enhancement
*P < 0.017 vs. normal group; §P < 0.017 vs. NIDCM (T2DM −) group