(A) Tensor visualization of the perforant path (indicated by yellow arrows) overlaid on a FA map. After Yassa et al., PNAS 2010; 107(28):12687-91, Fig. 1D, reprinted with permission. (B) comparison of perforant path diffusion signal in young vs. old showing a significant difference in area under the curve. After Yassa et al., PNAS 2010; 107(28):12687-91, Fig. 3, reprinted with permission, (C) correlation between perforant path integrity (operationalized as area under the curve) and delayed verbal recall in older adults. Adapted from Yassa et al., PNAS 2010; 107(28):12687-91 with permission.