. 2022 Jun 2;10:e13524. doi: 10.7717/peerj.13524

Table 1. Inhibitory effect of cardenolides ouabain, calotropin, and corotoxigenin 3-O-glucopyranoside on the enzymatic activity of Na⁺/K⁺-ATPase.

Compound	Inhibition of Na⁺/K⁺-ATPase IC₅₀ (μM)^a ± SD
Ouabain^b	0.12 ± 0.02
Calotropin	0.27 ± 0.06
Corotoxigenin 3-O-glucopyranoside^*	0.87 ± 0.2

Notes:

Half maximal inhibitory. The results are expressed as IC₅₀ ± standard deviation.

Ouabain was used as a positive control of inhibition of Na⁺/K⁺-ATPase.

Significative differences (p < 0.05) compared with the reference compound ouabain.

Table 1. Inhibitory effect of cardenolides ouabain, calotropin, and corotoxigenin 3-O-glucopyranoside on the enzymatic activity of Na+/K+-ATPase.