Table 1.
Study (first-named author) | Country | −592 | −819 | −1082 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genotype for cases | Genotype for controls | Genotype for cases | Genotype for controls | Genotype for cases | Genotype for controls | ||||||||
CC + CA | AA | CC + CA | AA | CC + CT | TT | CC + CT | TT | GG | GG + AA | GG | GA + AA | ||
Afzal [23] | Pakistan | – | – | – | – | 73 | 16 | 84 | 15 | 15 | 74 | 3* | 96 |
Dogra [25] | India | – | – | – | – | – | – | – | – | 38 | 32 | 42* | 28 |
Gao [21] | China | 35 | 20 | 40 | 35 | – | – | – | – | 2 | 53 | 1* | 73 |
Chuang [12] | Taiwan | 70 | 73 | 69 | 65 | 71 | 72 | 69 | 65 | 0 | 143 | 0* | 133 |
Bouzgarrou [13] | Tunisia | – | – | – | – | – | – | – | – | 19 | 81 | 12 | 91 |
Abbas [14] | Pakistan | 87 | 12 | 57 | 5 | 87 | 12 | 57 | 5 | 17 | 82 | 9 | 53 |
Pereira [6] | Brazil | 110 | 18 | 84 | 10 | 110 | 18 | 84 | 10 | 17 | 111 | 13 | 81 |
Chen [15] | Taiwan | 36 | 36 | 87 | 93 | 36 | 36 | 86 | 94 | 0 | 72 | 0* | 180 |
Falleti [22] | Italy | 21 | 29 | 35 | 61 | – | – | – | – | 8 | 42 | 25 | 71 |
Persico [16] | Ireland | 218 | 10 | 104 | 6 | 218 | 10 | 104 | 6 | 74 | 154 | 18 | 92 |
Mangia [20] | Italy | 246 | 24 | 136 | 9 | 246 | 24 | 136 | 9 | 40 | 230 | 23 | 122 |
Zein [19] | USA | 29 | 1 | 33 | 3 | 29 | 1 | 33 | 3 | 12 | 18 | 6 | 30 |
Egypt | 20 | 2 | 41 | 3 | 20 | 2 | 41 | 3 | 5 | 17 | 14 | 30 | |
Lio [18] | Italy | – | – | – | – | – | – | – | – | 27 | 33 | 34* | 101 |
Vidigal [17] | Ireland | 69 | 9 | 33 | 3 | 69 | 9 | 33 | 3 | 27 | 51 | 6 | 30 |
The distribution of genotypes in controls was not consistent with Hardy–Weinberg equilibrium law (P < 0·0001).