Table 2.
Crude (unadjusted) cognitive status measures according to peripheral neuropathy status among ARIC participants at visit 6 (2016–2017)
| Overall |
No Diabetes |
Diabetes |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| No PN (N=2044) | With PN (N=1318) | P-value | No PN (N=1435) | With PN (N=856) | Pvalue | No PN (N=609) | With PN (N=462) | P-value | |
|
| |||||||||
| Cognitive status | <0.001 | <0.001 | 0.035 | ||||||
| Normal (N = 2550) | 79.4% | 70.3% | 80.0% | 69.7% | 78.0% | 71.5% | |||
| Mild impairment (N = 630) | 16.7% | 21.9% | 16.5% | 22.1% | 17.4% | 21.4% | |||
| Dementia (N = 182) | 3.9% | 7.8% | 3.5% | 8.2% | 4.6% | 7.1% | |||
| Global z-score, mean (SD) | −0.21 (0.94) | −0.45 (0.98) | <0.001 | −0.17 (0.95) | −0.47 (0.98) | <0.001 | −0.29 (0.92) | −0.42 (0.98) | 0.027 |
| Executive functioning, z-score, mean (SD) | −0.23 (1.25) | −0.64 (1.36) | <0.001 | −0.18 (1.23) | −0.63 (1.36) | <0.001 | −0.36 (1.29) | −0.66 (1.36) | <0.001 |
| Language, z-score mean (SD) | −0.21 (1.11) | −0.36 (1.19) | <0.001 | −0.18 (1.12) | −0.36 (1.20) | <0.001 | −0.30 (1.08) | −0.36 (1.18) | 0.41 |
| Memory, z-score mean (SD) | −0.18 (1.23) | −0.37 (1.22) | <0.001 | −0.17 (1.25) | −0.44 (1.23) | <0.001 | −0.20 (1.19) | −0.24 (1.19) | 0.61 |
a
Includes trail making test parts A and B, digital symbol substitution, and digit span backwards tests
b
Includes word fluency, animal fluency, and Boston naming tests
c
Includes delayed word recall, logical memory, and incidental learning tests