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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Mol Psychiatry. 2022 Apr 1;27(6):2813–2820. doi: 10.1038/s41380-022-01526-6

Figure 4. GCAT exacerbates Amyloid-β mediated toxicity in vivo.

Figure 4.

(A) Co-expression of NSun2 RNAi (n = 17) with human Amyloid-β1–42 exacerbated the rough eye phenotype compared with that observed in the GFP RNAi control (n = 19). The yellow marked area shows degenerated part of eyes. (B) Histograms show quantitative assessment of eye phenotypes (****p-value=4.84E-09 by Mann-Whitney U test). Data represent mean ± standard error.