TABLE 1.
Oxidation of [14C]MeBr, [14C]methanol, or [14C]formaldehyde by glucose-grown strain IMB-1 cells in 15 min with or without preexposure to 18 μM MeBr for 6 h
| Substratea | Exposed to MeBr
|
Without Preexposure
|
||
|---|---|---|---|---|
| pmol/106 cells/hb | % Oxidized | pmol/106 cells/hb | % Oxidized | |
| MeBr | 1.04 (0.16) | 32 | 0.29 (0.05) | 9 |
| Methanol | 0.10 (0.03) | 6 | 0.09 (0.02) | 5 |
| Formaldehyde | 0.80 (0.18) | 45 | 0.76 (0.26) | 46 |
a
Substrate concentrations were all ∼2.7 (±0.1) μM.
b
Values represent the average of two cell suspensions, and values in parentheses indicate the range; cell densities were equal to 5.8 × 109 cells/ml; cells were taken through five transfers on glucose-based medium prior to exposure to MeBr.