Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 6;8:53. doi: 10.1038/s41421-022-00419-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — a Side and top views of cryo-EM map of untreated S protein. The three protomers of S protein are shown in light green, yellow, and sky blue. The three RBD domains are highlighted in Sea Green, gold, and deep sky blue, respectively. Glycosylation modifications are colored in tomato. b Side and top views of cryo-EM map of CTSL-treated S protein in different states. The map colors are as same as a. c The four structures of S proteins are superposed together in different colors. CS-1 and CS-2 sites are colored in red and as indicated. The CS-1 and CS-2 regions are zoomed in to show the details. The cleavage sites are indicated by the red lighting-shaped symbol. For untreated S protein, the electron density around the cleavage site is represented as black grid. For the CTSL-treated S, the cleavage site cannot be traced and is represented as dotted line.