Table 2.
Comparison of GMM model and STEPS with conventional clinic-based and patient-reported outcomes.
| Adjusted R2 | EDSS | TUG | T25FW | 2MWT | MSWS−12 |
|---|---|---|---|---|---|
| GMM | 0.557 | 0.536 | 0.489 | 0.560 | 0.383 |
| STEPS | 0.465 | 0.419 | 0.402 | 0.432 | 0.378 |
| GMM + STEPS | 0.631 | 0.541 | 0.503 | 0.542 | 0.446 |
| GMM (Adjusted) | 0.675 | 0.587 | 0.546 | 0.538 | 0.512 |
| STEPS (Adjusted) | 0.569 | 0.525 | 0.453 | 0.439 | 0.461 |
| GMM + STEPS (Adjusted) | 0.710 | 0.583 | 0.544 | 0.548 | 0.533 |
EDSS, Expanded Disability Status Score; TUG, Timed-Up-and Go Test; T25FW, Timed-25 Foot Walk test; 2MWT, 2-min Walk Test; MSWS-12, 12-item MS Walking Scale. GMM - Normal 3 Mixture; STEPS, Average daily step count over the first 4 weeks (or 28 days). (Adjusted for = sex; age; and disease duration into the model).