Table 3.
Echocardiographic parameters of left heart in Han lowlanders, Han migrants and native Tibetans.
|
Han lowlanders (n = 82) |
Han migrants <1 year (n = 64) |
Han migrants > 5 years (n = 71) |
Tibetans (n = 75) |
p | |
|---|---|---|---|---|---|
| Conventional and Doppler data | |||||
| LA EDVI (ml/m2) | 20.3 ± 4.4 | 16.9 ± 3.3* | 17.1 ± 3 | 17.8 ± 3.8 | 0.000 |
| LA ESVI (ml/m2) | 7 ± 1.6 | 6.7 ± 1.8 | 6.6 ± 1.8 | 7.6 ± 1.9‡ | 0.017 |
| LAEF (%) | 65.3 ± 5.3 | 60.3 ± 6.9* | 61.7 ± 7.7 | 57.5 ± 6.2‡ | 0.000 |
| LA GLS (%) | 42.6 ± 7.1 | 40.2 ± 4.7 | 40.5 ± 6.9 | 38.8 ± 6.6 | 0.000 |
| IVST (mm) | 8.5 ± 1.1 | 8.7 ± 1.4 | 9.5 ± 1.1† | 7 ± 1.1‡ | 0.000 |
| LVDD (mm) | 49.7 ± 4.8 | 41.7 ± 3.1* | 42.5 ± 2.3 | 46.1 ± 3.6‡ | 0.000 |
| LVPWT (mm) | 7.3 ± 0.8 | 8.1 ± 1.4* | 8.8 ± 1† | 6.7 ± 1.1‡ | 0.000 |
| Mitral E (cm/s) | 85.2 ± 10.8 | 64.2 ± 11.2* | 59.8 ± 9.2† | 77.9 ± 10.3‡ | 0.000 |
| Mitral A (cm/s) | 45.2 ± 6.5 | 50.1 ± 7.1* | 46.9 ± 8.1† | 48.4 ± 9.2 | 0.000 |
| Mitral E/A ratio | 1.8 ± 0.2 | 1.6 ± 0.3 | 1.3 ± 0.2† | 1.7 ± 0.2‡ | 0.000 |
| e′ (cm/s) | 17.6 ± 2 | 16 ± 2.8* | 14.3 ± 2† | 18.5 ± 1.8‡ | 0.000 |
| a′ (cm/s) | 7.6 ± 1.4 | 8.1 ± 1.6 | 9 ± 1.8† | 7 ± 1‡ | 0.000 |
| Mitral E/e′ ratio | 5.2 ± 1.3 | 4.1 ± 1* | 4.2 ± 0.7 | 4.8 ± 1.3‡ | 0.000 |
| IVRT (ms) | 62.9 ± 5 | 73.2 ± 6.8* | 80.8 ± 7.4† | 82 ± 8.8 | 0.000 |
| DT (ms) | 171.3 ± 26.5 | 177.6 ± 23.8* | 189 ± 21.4† | 157.7 ± 14.2‡ | 0.000 |
Values are means ± SD. *P < 0.05 short-term acclimatized Hans vs. lowlanders; P < 0.05 long-term acclimatized Hans vs. short-term acclimatized Hans; P < 0.05 Tibetans vs. long-term acclimatized Hans.
EDVI, end-diastolic volume index; EDVI, end-systolic volume index; LAEF, left atrial emptying fraction; GLS, global longitudinal strain; IVST, interventricular septal thickness LVDD, left ventricular end diastolic diameter; LVPWT, left ventricular posterior wall thickness; IVRT, isovolumic relaxation time; DT, deceleration time.