MASTL depletion influences stem-cell-associated surface proteins
(A) Experimental outline for stable isotope labeling with amino acids in cell culture (SILAC)-based proteomics of surface proteins (surfaceome) in heavy and light isotope-labeled siControl- and siMASTL-treated cells.
(B) Significantly altered surface proteins in MASTL-silenced cells (SILAC siMASTL/siControl Ratio (log2) >0.5/<-0.5 and FDR <0.05) and functional enrichment based on g-Profiler (Raudvere et al., 2019). See also Figure S4 and Table S1.