Table 1.
Mass spectrometric settings for MRM of the analytes and internal standards.
| Compounds | Precursor ion (m/z) | Product ions (m/z) |
|
|---|---|---|---|
| Quantification ion | Confirmation ion | ||
| CML | 205 | 84 | 130 |
| d4-CML* | 209 | 88 | 134 |
| CEL | 219 | 84 | 130 |
| d4-CEL* | 223 | 88 | 134 |
| HMF | 127 | 109 | 81 |
| 13C6-HMF* | 133 | 115 | 86 |
| QD of GO | 131 | 77 | 51 |
| QD of MGO | 145 | 77 | 92 |
| QD of 3-DG | 253 | 171 | 199 |
| 5-methylquinoxaline* | 145 | 91 | 65 |
Abbreviations: CML, Nε-(carboxymethyl)lysine; CEL, Nε-(carboxyethyl)lysine; HMF, 5-hydroxymethylfurfural; QD, Quinoxaline Derivative. Compounds marked with an asterisk (*) serve as internal standards.