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. 2022 May 23;12:859721. doi: 10.3389/fonc.2022.859721

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Copyright © 2022 Zhong, Wei, Liao, Wang, Peng, Zhou, Huang, Xian, Peng, Zhang, Feng, Liu, Hong, Xia, Yan, Liu and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distinct microbiome composition between the NPC group and the control group. Taxonomic composition in the NPC group and the control group exhibits average relative abundance at the phylum (A) and genus (B) levels. (C) Differential taxa from phylum to species were identified by LEfSe with a meeting LDA significant value (LDA > 2, red color indicating taxa abundant in the control group; green in the NPC group). (D) Cladogram shows the differential taxa at all levels from phylum to species. (E) Differential taxa at the genus level are represented (LDA > 2, red color indicating taxa enriched in the control group; green in the NPC group).