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. 2022 May 23;12:859721. doi: 10.3389/fonc.2022.859721

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Copyright © 2022 Zhong, Wei, Liao, Wang, Peng, Zhou, Huang, Xian, Peng, Zhang, Feng, Liu, Hong, Xia, Yan, Liu and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential genera and metabolic function pathways associated with NPC and chronic nasopharyngitis. (A) A heatmap shows the relative abundance of significant genera between the NPC group and the control group (Mann–Whitney tests, unadjusted p value < 0.05). (B) Differential genera in relative abundance detected by a MaAsLin model with adjustment for age are exhibited (* means corrected Q value < 0.25). (C) ROC curve analysis of differential genera for diagnosis of NPC from chronic nasopharyngitis. (D) Distinct metabolic pathways compared between NPC and chronic nasopharyngitis based on KEGG with FDR corrected p value (Q value < 0.05).