Table 2.
Characteristics and univariate analysis of PFS in the participants with NPC.
| Covariates | R (n = 32) | NR (n = 10) | p value | Univariate analysis | |
|---|---|---|---|---|---|
| HR (95% CI) | p value | ||||
| Age (years) | 48.8 ± 7.4 | 57.7 ± 13.3 | 0.068 | 1.087 (1.01, 1.12) | 0.023 |
| Gender | 0.606 | ||||
| Male | 24 (75.0) | 6 (60.0) | Reference | ||
| Female | 8 (25.0) | 4 (40.0) | 1.34 (0.37, 4.77) | 0.656 | |
| Smoker | 0.117 | ||||
| No | 18 (56.2) | 9 (90.0) | Reference | ||
| Yes | 14 (43.8) | 1 (10.0) | 0.10 (0.01, 0.85) | 0.035 | |
| Alcohol abuse | 1.000 | ||||
| No | 28 (87.5) | 9 (90.0) | Reference | ||
| Yes | 4 (12.5) | 1 (10.0) | 0.60 (0.07, 4.90) | 0.635 | |
| Clinical stage | 0.001 | ||||
| I + II + III | 26 (81.2) | 2 (20.0) | Reference | ||
| IVa + IVb | 6 (18.8) | 8 (80.0) | 7.66 (1.61, 36.43) | 0.011 | |
| Dubosiella | 1.69 (1.16, 2.48) | 0.007 | |||
| Bifidobacterium | 3.78 (1.45, 9.87) | 0.006 | |||
| Turicibacter | 5.11 (2.04, 12.77) | <0.001 | |||
| Clostridium_sensu_stricto_1 | 1.06 (1.01, 1.11) | 0.012 | |||
The values are presented as the mean ± standard deviation (SD) or n (%) unless otherwise stated.
R, Patients without progressive disease after standard treatments; NR, Patients with progressive disease after standard treatments. p < 0.05 (the bold values) in the table indicates a statistical significance.