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(A) Treatment approach for patients with kaposiform hemangioendothelioma. KHE, kaposiform hemangioendothelioma; KMP, Kasabach-Merritt phenomenon; SIR, sirolimus; VCR, vincristine. (B) Treatment approach for patients with complicated vascular malformations. *Steady state is defined as a stable disease in two consecutive MRT volumetries at least 6 months apart.
