Table 4.
Description of the number of adverse effects in each selected study in meta-analysis.
| Detailed type of AEs | Pedapati et al. (14) | Ameis et al. (10) | Fecteau et al. (13) |
Enticott et al. (6) |
Jannati et al. (15) | Ni et al. (26) | Baruth et al. (27) | Yang et al. (28) | Gwynette et al. (29) | Oberman et al. (30) | Dang et al. (31) | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total number of participants in active group | 9 | 20 | 10 | 15 | 11 | 19 | 16 | 11 | 10 | 19 | 12 | 152 |
| Total number of participants that experienced adverse effects | 1 | 8 | 6 | 3 | 1 | 3 | 6 | 3 | 3 | 3 | 3 | 40 |
| Itching | 5 | 5 | ||||||||||
| Irritability | 3 | 1 | 3 | 7 | ||||||||
| Headache | 1 | 4 | 1 | 1 | 1 | 8 | ||||||
| Sleepy | 3 | 3 | ||||||||||
| Headedness/dizziness | 1 | 1 | 2 | |||||||||
| Facial discomfort | 2 | 3 | 5 | |||||||||
| Mild scalp irritation | 1 | 1 | ||||||||||
| Pain at application site | 1 | 1 | 2 | |||||||||
| Neck pain | 1 | 1 | ||||||||||
| Nausea | 1 | 1 | ||||||||||
| Improved mood | 3 | 3 | ||||||||||
| Trouble concentrating | 2 | 2 | ||||||||||
| More emotional | 1 | 1 | ||||||||||
| Transient muscle spasms | 1 | 1 | ||||||||||
| Seizure due to a programming error | 1 | 1 | ||||||||||
| Fatigue | 2 | 2 | ||||||||||
| Stiff neck | 2 | 2 | ||||||||||
| Subtle disorientation | 1 | 1 | ||||||||||
| Improved concentration | 1 | 1 | ||||||||||
| Other | 1 | 1 |