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. 2022 Jul;231:106437. doi: 10.1016/j.actatropica.2022.106437

Table 3.

Impact of mass drug administration on lymphatic filariasis infection parameters.

Treatment Zone Timing of the survey Number of participants (N) CFA prevalence(95% CI) Mf prevalence(95% CI) Geometric mean Mf/mL Community Mf load (CMFL)
Annual MDA BaselineA 997 12.5 (10.5, 14.8) 1.6 (0.8, 2.5) 59.4 (27.3, 129.2) 3.9 (3.3, 4.7)
Follow-up 1A 639 6.1 (4.4, 8.2) 0 (0.0, 0.6) N/A N/A
Follow-up 2B 898 1.8 (1.0, 2.9) 0 (0.0, 0.4) N/A N/A
Follow-up 3A,B 1066 1.2 (0.7, 2.1) B 0 (0.0, 0.3) N/A N/A
Follow-up 4B,C ND ND ND ND ND
Semiannual MDA BaselineA 1169 13.6 (11.7, 15.7) 1.7 (0.7, 2.1)
65.8 (37.4, 116.0)

4.1(3.6, 4.6)
Follow-up 1A 1174 10.1 (8.4, 11.9) 0.2 (0.003, 0.06) N/A N/A
Follow-up 2B 1132 3.3 (2.3, 4.5) 0 (0.0, 0.3) N/A N/A
Follow-up 3A,B 1209 4.2 (3.2, 5.5) B 0 (0.0, 0.3) N/A N/A
Follow-up 4B,C 1748 2.6 (2.0, 3.5) 0 (0.0, 0.2) N/A N/A

ND, Not done. N/A, Not applicable.

Villages in the Center received annual MDA while villages in the North received semiannual MDA.

A

Circulating filarial antigenemia (CFA) was detected by ICT.

B

CFA was detected by FTS.

C

Both treatment zones received once/year MDA from the Liberia Ministry of Health from months 36 to 60.