Table 3.
Impact of mass drug administration on lymphatic filariasis infection parameters.
| Treatment Zone | Timing of the survey | Number of participants (N) | CFA prevalence(95% CI) | Mf prevalence(95% CI) | Geometric mean Mf/mL | Community Mf load (CMFL) |
|---|---|---|---|---|---|---|
| Annual MDA | BaselineA | 997 | 12.5 (10.5, 14.8) | 1.6 (0.8, 2.5) | 59.4 (27.3, 129.2) | 3.9 (3.3, 4.7) |
| Follow-up 1A | 639 | 6.1 (4.4, 8.2) | 0 (0.0, 0.6) | N/A | N/A | |
| Follow-up 2B | 898 | 1.8 (1.0, 2.9) | 0 (0.0, 0.4) | N/A | N/A | |
| Follow-up 3A,B | 1066 | 1.2 (0.7, 2.1) B | 0 (0.0, 0.3) | N/A | N/A | |
| Follow-up 4B,C | ND | ND | ND | ND | ND | |
| Semiannual MDA | BaselineA | 1169 | 13.6 (11.7, 15.7) | 1.7 (0.7, 2.1) |
65.8 (37.4, 116.0) |
4.1(3.6, 4.6) |
| Follow-up 1A | 1174 | 10.1 (8.4, 11.9) | 0.2 (0.003, 0.06) | N/A | N/A | |
| Follow-up 2B | 1132 | 3.3 (2.3, 4.5) | 0 (0.0, 0.3) | N/A | N/A | |
| Follow-up 3A,B | 1209 | 4.2 (3.2, 5.5) B | 0 (0.0, 0.3) | N/A | N/A | |
| Follow-up 4B,C | 1748 | 2.6 (2.0, 3.5) | 0 (0.0, 0.2) | N/A | N/A |
ND, Not done. N/A, Not applicable.
Villages in the Center received annual MDA while villages in the North received semiannual MDA.
Circulating filarial antigenemia (CFA) was detected by ICT.
CFA was detected by FTS.
Both treatment zones received once/year MDA from the Liberia Ministry of Health from months 36 to 60.