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. 2022 May;345:190–199. doi: 10.1016/j.jconrel.2022.03.008

Table 4.

Model predictions specified to the treatment protocol of Conley et al. [33] presenting the total population of immune cells (NK cells, CD8+ T-cells, conventional CD4+ T-cells and Tregs), macrophages and VEGF concentration (dimensionless). The cell population is normalized by division with the initial number of non-stem cancer cells. The parameters were calculated midway between the tumor center and periphery.

Treatment Immune cells M1-like TAMs M2-like TAMs VEGF
Control 6.83 0.073 0.383 0.34
CRLX101 (with normalization) 17.65 0.234 0.081 0.12
CRLX101(without normalization) 10.18 0.141 0.154 0.21