Fig. 7.

In vivo biocompatibility evaluations with implantation of FV-60A IOL (Group I), PUA-BLK IOL (Group II) and PUA-GAT IOL (Group III): (A) Slit-lamp examination of anterior segment at different time points, slight inflammation including conjunctival injection, chemosis, corneal edema, aqueous flare, and presence of cells in aqueous humor was demonstrated in all group at the early stage after surgery, no severe inflammation was seen postoperatively; (B) Histological images of cornea, iris and retina on day 29 after implantation, regular and intact structures were found in all groups and no sign of severe inflammation was noticed, scale bar: 100 μm; (C) Corneal endothelial cell density pre-operation and on day 29 after implantation (P > 0.05, multiple t tests); (D) GAT concentration from PUA-GAT IOL and from topical GAT gel in aqueous humor (AH), wherein the horizon lines (in red and orange) represent two MIC₉₀ of GAT towards S. epidermidis according to references.