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. 2022 Jun 6;10(7):e648. doi: 10.1002/iid3.648

Figure 1.

Figure 1

CD200 is reduced in PN skin. (A) CD200 QPCR on healthy (NN), non‐lesional (PN), and lesional (PP) psoriasis skin relative to the mean NN value. (B) Flow cytometry showing CD200 (black line) and isotype control (gray filled histograms) on NN and PN skin. (C−E) Immunohistochemistry showing: (C) CD200 in NN and PN skin with a secondary only control, and blockade of the anti‐CD200 signal by prior incubation with soluble CD200, (D) pDok1 costaining with CD200 or CD200R1 in NN skin, (E) pDok1 in NN and PN skin. Bar charts show all data (n = 4−6), Mean and SD shown. (A) was analyzed by ordinary analysis of variance and Dunnett's test. (B, C) and (E) were analyzed by Mann−Whitney test. *p < .05. PN, non‐lesional psoriasis; PP, psoriasis plaque; QPCR, quantitative polymerase chain reaction.