Table 1.

Summary of Fe-NTA-induced renal carcinogenesis experiments in rats.

	Untreated control		Fe-NTA-induced renal carcinogenesis protocol
	Wild-type	Brca1(L63X/+)	Wild-type	Brca1(L63X/+)
Total renal cell carcinoma (RCC)	0/20	0/21	17/20 (85.0%)	17/19 (89.5%)
RCC with pulmonary metastasis	0/0	0/0	8/17 (47.1%)	6/17 (35.3%)
RCC with peritoneal invasion/dissemination	0/0	0/0	6/17 (35.3%)	9/17 (52.9%)

Fe-NTA, ferric nitrilotriacetate; Brca1(L63X/+), Brca1 mutant (heterozygously knockout) rat. Refer to text for details.