Table 2.
Response of the Tumor to Radiofrequency Ablation in Relation to the Clinical, Biochemical, Radiological, and Pathological Parameters.
| Parameter | Tumor Response to RFA |
P Value | Test of Significance | |
|---|---|---|---|---|
| Responder (n = 36) | Nonresponder (n = 14) | |||
| Age | ||||
| Range | 41–75 | 46–72 | ||
| Median | 54.50 | 51.50 | P = 0.279 | U = 202.00 |
| Mean ± SD | 56.22 ± 7.885 | 54.14 ± 7.702 | ||
| Gender | ||||
| Male | 32 (88.9%) | 10 (71.4%) | FEP = 0.197 | – |
| Female | 4 (11.1%) | 4 (28.6%) | ||
| Child-Turcotte-Pugh class | ||||
| A | 2 (22.2%) | 2 (40.0%) | FEP = 0.580 | – |
| B | 7 (77.8%) | 3 (60.0%) | ||
| Serum alpha-fetoprotein | ||||
| Range | 1–2000 | 5.42–815 | ||
| Median | 40.00 | 109.00 | P = 0.027∗ | U = 149.50 |
| Mean ± SD | 126.45 ± 333.051 | 220.48 ± 253.149 | ||
| Number of tumors | ||||
| Mean value | 1.36 ± 0.683 | 1.71 ± 0.726 | P = 0.056 | U = 178.00 |
| Distribution: | ||||
| 1 nodule | 27 (75.0%) | 6 (42.9%) | ||
| 2 nodules | 5 (13.9%) | 6 (42.9%) | P = 0.064 | χ2 = 5.507 |
| ≥3 nodules | 4 (11.1%) | 2 (14.3%) | ||
| Size of tumors | ||||
| Mean value | 3.31 ± 0.905 | 3.10 ± 0.875 | P = 0.579 | U = 220.00 |
| Distribution: | ||||
| <2 cm | 2 (5.6%) | 1 (7.1%) | ||
| 2–3 cm | 14 (38.9%) | 6 (42.9%) | P = 0.933 | χ2 = 0.140 |
| >3 cm–≤5 cm | 20 (55.6%) | 7 (50.0%) | ||
| Pathological grade of tumors | ||||
| Grade I | 9 (25.0%) | 0 (0.0%) | ||
| Grade II | 24 (66.7%) | 7 (50.0%) | P = 0.002∗ | χ2 = 12.702 |
| Grade III | 3 (8.3%) | 7 (50.0%) | ||
U: Mann–Whitney test.
χ2: Chi-square test.
FE: Fisher’s Exact test.
P: P value for association between different categories.
∗: Statistically significant at P ≤ 0.05.