Table 2.
Univariate and Multivariable Logistic Regression Analysis of the Association of AFP Levels With Portal Vein Tumor Thrombosis (PVTT).
| Variable | PVTT |
P value | OR (95% CI) (univariate) | OR (95% CI, P value) (multivariate) | |
|---|---|---|---|---|---|
| Absent n = 274 | Present n = 234 | ||||
| Gender | 0.0471 | ||||
| Female | 42 (15.3%) | 22 (9.4%) | Ref | ||
| Male | 232 (84.7%) | 212 (90.6%) | 1.74 (1.01–3.01) | 1.69 (0.95–3.01,P = 0.07) | |
| Age | 0.0341 | ||||
| ≤40 | 32 (11.7%) | 43 (18.4%) | 1.70 (1.03–2.79) | 1.30 (0.76–2.21,P = 0.335) | |
| >40 | 242 (88.3%) | 191 (81.6%) | Ref | ||
| Etiology | 0.0431 | ||||
| NBNC | 119 (43.4%) | 81 (34.6%) | Ref | ||
| HBHC | 155 (56.6%) | 153 (65.4%) | 1.45 (1.01–2.08) | 1.31 (0.89–1.92,P = 0.174) | |
| AFP(ng/ml) | |||||
| (mean ± SD) | 36314.2±128780.1 | 106346.9±300565.7 | <0.0012 | ||
| AFP(ng/ml) | |||||
| <10 | 71 (25.9%) | 21 (9%) | Ref | ||
| 10–400 | 90 (32.8%) | 56 (23.9%) | 2.10 (1.16–3.79, P = 0.014) | 2.00 (1.09–3.66,P = 0.024) | |
| >400 | 113 (41.2%) | 157 (67.1%) | 4.69 (2.73–8.09, P < 0.001) | 4.08 (2.34–7.12,p=<0.001) | |
| AFP(ng/ml) | <0.0011 | ||||
| ≤400 | 161 (58.8%) | 77 (32.9%) | Ref | ||
| >400 | 113 (41.2%) | 157 (67.1%) | 2.91 (2.02–4.18) | 4.08 (2.34–7.12,p=<0.001) | |
| MTD (cm) | <0.0011 | ||||
| ≤5 | 68 (24.8%) | 20 (8.5%) | Ref | ||
| >5 | 206 (75.2%) | 204 (91.5%) | 3.53 (2.07–6.02) | 2.89 (1.66–4.88,P value=<0.001) | |
All values: Means ± Standard Deviation as continuous; Frequencies and percentage (%) as categorical.
1.Chi-square test 2.Mann–Whitney U test.
MTD (Maximum tumor diameter); AFP (Alfa-fetoprotein); HBHC (Hepatitis B and hepatitis C); NBNC (Nonhepatitis B and non-hepatitis C).